Monday, July 10, 2023

Doing a Postmortem on the Pandemic

I ran across an interesting piece by Matthew Yglesias, What I got wrong about Covid - by Matthew Yglesias (slowboring.com).  It sparked an examination of what we did right, and what we did wrong, during the pandemic. Covid isn't over yet, but we are past what we would call the pandemic phase.

From the article:

"The SARS-CoV-2 pandemic left a lot of obvious scars on the country — death, Long Covid cases, lost jobs, shuttered businesses, and the loss of valuable learning time in school..."

Yglesias said, "My goal in this piece is to recount the evolution of my own thinking in an honest way, reflecting on what I think I got right and on my current retroactive view of things, but also owning up to the fact that, like most people, I was making assessments in real-time with imperfect information and minimal experience. In other words, what I got wrong...As the events of February 2020 played out, it became clear to me that the pandemic was going to go global (the correct call) and my view was that basically nothing would be done to halt it (incorrect)."

"I thought the pandemic would play out essentially as it did in March of 2020. The virus was spreading rapidly in the tri-state area and as governors there imposed heavy restrictions, many of the region’s more skeptical residents departed for Florida. Ron DeSantis responded by trying to impose mandatory quarantines to prevent northern transplants from spreading the virus locally."

"...My thought was that during the peak of the crisis, it might be important to shut ourselves up at home for a while, so I went to Costco to stockpile stuff — dried pasta, jars of Rao’s, frozen vegetables, canned beans, over the counter medicine, first-aid supplies (including surgical masks), bottles of water and purification tablets, batteries, and everything else we’d need to ride out a disaster....Meanwhile, I was waiting to ride out an inevitable crisis because I didn’t expect any policy response at all."

"...It was soon after this that I learned about the idea of flattening the curve.

The idea — which I think is still underrated — is essentially harm reduction for pandemics. The point is that while there probably isn’t a cost-effective way to prevent a new disease from coming to your city, you can avoid the crisis situation I was worried about and make sure that everyone who’s sick gets treated.  The way you achieve this, to quote a March 10 Vox graphic, is by trying to impose enough restrictions on activity to slow the spread of the virus and distribute the caseload over time. This ensures that everyone who needs treatment gets treatment and prevents the infection fatality rate from soaring."

"My worst call of the year, though, came about six weeks after that piece ran when I got a bad case of Taiwan envy and called for the United States to try to emulate Asian-style total suppression of the virus."

I think that if you read the specific arguments of that piece, it sort of makes sense. I was saying, basically, that a super-intense total suppression lockdown could be relatively brief and then allow more freedom (as well as more lives saved) than a prolonged period of curve-flattening. But it was totally detached from political reality. Not only was the consensus in favor of pandemic-halting action already breaking down in conservative areas, but progressives would never in a million years license things like cops kicking in doors to bust up illegal house parties.

I pretty soon started writing more pragmatic pieces about how we should reopen parks and encourage people to do stuff outside (April 30) and make reopening schools in the fall of 2020 a top priority in our social and economic planning (May 28)....

...But what I never did while I was still at Vox was write clearly about how, in practice, that all meant giving up on suppression and returning to curve-flattening as a standard."

"....Once vaccines were approved in November 2020, I think I consistently had the correct high-level view:  

  • "It made sense to be very cautious in your personal behavior until you could get the vaccine.  

  • "It made sense to have a simple prioritization scheme for scarce doses — give it to old people — so as to maximize benefits.  

  • "Vaccination reduced society-level vulnerability so much that it made sense to lift all restrictions once the shots were widely available.

  • "In curve-flattening terms, the point was that a highly vaccinated population was just extremely unlikely to develop crisis-level case volumes. The benefits of non-pharmaceutical interventions became much lower, while the costs remained high.

  • I was very frustrated, intellectually and emotionally, with school closures. I argued against closing schools before the vaccines were available, but had lost that argument internally to the politics of blue states. I wanted vaccination to be the game-changer that ended NPIs, so I expressed erroneous overconfidence about the vaccines’ ability to block transmission. And because I overestimated vaccines’ ability to block transmission, I overestimated the case on the merits for mandatory and quasi-mandatory means to promote vaccination. A lot of conservatives see arguments for vaccine mandates as an example of Covid hawk extremism, but I think a lot of us embraced them as an alternative to Covid hawk extremism."

  • ....But factually, though the vaccines are very useful, their impact on transmission (especially post-Delta) was limited. Mandates turned vaccination into a wedge issue that advantaged Republicans rather than Democrats.

  • "... looking back on it, I think the best course of action for the United States was the one embedded in that March 10 Vox article about curve-flattening. I really think it’s worth everyone’s time to revisit commentary from that early March 2020 era, because it’s strikingly different from what eventually emerged out of a very polarized debate. There’s no dismissal or denialism of the severity of the virus in the piece, none of Trump’s false assurances and none of the biting mockery of people for being concerned about it. But relative to what would later become the Covid hawk position, it’s incredibly moderate."

  • "...From a US standpoint, you want to prevent any place from becoming the next Wuhan,” said Tom Frieden, who led the CDC under President Barack Obama. “What that means is even if we’re not able to prevent widespread transmission, we want to prevent explosive transmission and anything that overwhelms the health care system.”

  • "...Importantly, the reason public health professionals converged on this curve-flattening idea in early March 2020 is that it’s what the pandemic response playbook written in the period between 9/11 and the swine flu scare of 2009 said we should do. Most of us did not pay a lot of attention to that pandemic planning work, but it resulted in some pretty good ideas and we should have stuck with them. I’m not 100% sure why we didn’t. ...But my best broad guess is that two factors drove the dysfunctional response. One is that Trump is an undisciplined guy whose go-to political move is driving polarization rather than consensus. The other is that social media totally wrecked America’s epistemic institutions....In the media, the number one constituency for clicking on and sharing Covid-related articles was the most neurotic super-doves, and the number two was nut-job conspiracy theorists."


  • A few personal notes; for us, at least, the strategy of mask wearing, getting vaccinated and boosted, and being cautious about exposure worked.  We eventually did get Covid in December of 2022.  But by that time it was the less dangerous Omicron version, and the antiviral Paxlovid was available if you were part of a vulnerable demographic, which we were, since we were over 65. 

  • Even though our governor had not always made the best decisions, he stuck with the strategy of curve flattening to avoid overwhelming the medical system.  It wasn't perfect, but it got our state through the worst of the pandemic.

  • I think as a society we need to let go of the idea that there was any perfect solution to this virulently contagious virus. What we should do is learn from it, in order to apply the lessons to the future.  This is something that perhaps AI could help with, to make sense of all the data, and develop strategies to deal with future virus breakouts to hopefully avoid a pandemic situation.



25 comments:

  1. I don't read Yglesias a lot, but I understand he is kind of a free-thinker who doesn't always perfectly align with progressive nor conservative orthodoxy. He comes close here to what I would describe as the reasonable-conservative position (as opposed to the Trumpy-conservative sham science). A lot of conservatives would argue that the mask-wearing wasn't actually all that effective, so mask mandates were a bridge too far. They would strongly agree with Yglesias that the school closings went on for way too long.

    As for the shuttering of businesses: perhaps some businesses suffered because of overreaction. But from a liberal-vs-conservative standpoint, it's worth recalling that the sudden shutdown of the retail economy in 2020 wasn't the result of overreaching government mandates; it was the result of a social consensus. Americans simply agreed to stop going out to shop for non-necessities. That hurt a lot of retail shops and restaurants, and killed off some of them.

    The social conflict came about more from the decisions regarding when and how much to reopen. At least, that's how I recall it.

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    1. Yeah, I don't read Yglesias a lot either. I just thought it was worth a look in the not -so- distant rear view mirror.
      About the mask wearing, at first it was all we had. Some masks definitely worked better than others if you used them right (having it pulled down below your nose was not the right way!) They weren't perfect, but much better than nothing. And same with school closings, we knew the disease was spread in crowds, and schools are a crowd. It was feared that a bunch of teachers would get sick, and some did, especially the older ones. And kids could carry the virus to vulnerable family members. So I'm not going to criticize the school closings too hard. The online learning didn't work too well for a lot of kids, though.

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    3. Sorry, I hit the submit button too soon so had to remove the comment directly above.

      I agree that shutting down schools was the right move, for the reasons you give. Where I think the conservative (and other) critics have a point is that, in some locales, they stayed shut down way too long. It's helpful to look at it in light of Yglesias's "flatten the curve" approach. Once the vaccines were widely available and the less virulent strains of COVID were dominant, it became difficult to justify keeping the schools shut down.

      And unfortunately, the prophets of doom seem to have been right about the negative education impact. It appears a lot of kids still haven't "caught up". One of the lessons that needs to be learned from the pandemic experience is that these public health measures involve trade-offs and unintended consequences. The law of diminishing returns probably applies: if we ratchet up the public-health restrictions another click or two, the public health benefits may be incremental (or minuscule), whereas the negative impacts in other areas could be substantial.

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    4. I think the kids who were most negatively affected by school closings were the ones who already had circumstances going against them, such as poverty or family problems.

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    5. Katherine - yes, or special learning needs.

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  2. In some ways, the challenge of COVID was a challenge about the virtue of solidarity. Everyone understands self-protection; that is why most of us agreed to wear masks, and wanted to get vaccinated. But the notion that each of us should do these things to protect others, beyond our families: a lot of Americans didn't buy into that. Or so it seems to me.

    Fwiw - I still see a few masks in our Sunday congregations. I assume those are people with health risks. I suppose some of them could be what Yglesias called "super-hawks". (Or are they "super-doves"? I'm not entirely clear what he means by those terms.)

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    1. I think you are right that the notion of solidarity didn't seem to take with a lot of people.
      I still do see a few people with masks around. I'm assuming most of them are immune compromised in some way. There are a few people who aren't in a good place emotionally due to the pandemic, and are afraid to be in a public space, and don't really go anywhere.

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  3. Knowing an ICU nurse that was transferred to a COVID ward during the pandemic, I know the hospitals were overwhelmed and that body bags were being filled left and right. Nothing was 100% effective, including the vaccines, which were not as effective as hoped. There's evidence in a Danish study that early batches of the Pfizer vaccine caused side effects like cardiomyopathy. The researcher had difficulty getting this published.

    https://youtu.be/KgldG9r-i9M

    Further, the DOE and FBI say it's possible that COVID originally leaked from the Wuhan lab, not the meat market.
    Possible serious sources of distortion in looking back on COVID, political motivation and enclosure of vaccine technology by corporations.

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    1. The thing about where the virus spread from, is that it could have come from either the market or the lab. Because they both were doing dangerous practices. They had a bunch of animals in the market caught in the wild, probably with feces and urine contaminating the area, that's how you get zoonotic spillover.
      And they were doing "gain of function" research in the lab, which seems pretty dangerous. I don't care if they're doing it for research, they're potentially making super bugs.

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  4. Hindsight is always great. Covid was the third leading cause of death in the US in both 2020 and 2021, after heart disease and cancer.:zero to sixty in a year.. I do wonder how much worse it might have been if we hadn’t worn masks and locked down - especially in 2020 and early 2021 before the vaccine was available in spring of 2021. In 2021 the mortality rate for those who got Covid but weren’t vaccinated was many multiples higher than for those who got Covid and had been vaccinated. It’s pretty easy to map the highest mortality states - they map pretty closely to vaccination rates. Florida was one. Arizona was hit hard in 2020 before vaccines and they only locked down and required masks for three weeks in May. They had to get refrigerated trucks to hold the bodies in Phoenix and Tucson after the morgues were full.Hospital beds pretty much disappeared and a lot of people died. My brother and his wife went back to normal life after masks and lockdowns were lifted and both got very sick from Covid. But they survived. My sister in law’s brother in Sedona died of Covid a few months later..

    Conservatives have been circulating a study that seems to show that masks don’t work. They’ve seized on one or two to bolster their arguments, conducted by a couple of right- wing scientists. But most legitimate studies show that good masks, worn properly, ( as Katherine notes) do help dramatically. I’m not sure I would feel comfortable having surgery with unmasked doctors and nurses! There is a reason they mask themselves also when around patients with dangerous communicable diseases.

    Closing schools was a real dilemma - nobody actually knew what the impact would be. And the pandemic was a once in a century thing ( we hope). Learn by trying different things as you go along.

    For kids in our grandson’s private school with an average of 13 kids/class and parents working from home who could keep their kids on task, the kids did fine. In large public schools, especially with parents who were in the service economy, unable to stay home to supervise online schooling, the kids fell behind. The big dilemma was keeping more vulnerable teachers and staff safe - quite a few teachers died from Covid. And children couldn’t be vaccinated yet.

    I recently read that some scientists estimate that 95% of Americans have had Covid. I have never had it, although my husband has. All three sons, all seven grandchildren, and two of three daughters in law have had Covid. All mild cases because post- vaccine. I live normally now - usually no masks, flying on planes ( but we still mask on planes). Our doc suggested getting another bivalent shot this summer and the new vaccine in late fall. He didn’t get Covid either until sometime in the last few months.I had asked him if I might have had it without knowing. He said he had thought that about himself - until he got it. So he thinks that I am among the small number of Americans who hasn’t yet gotten it. However, we live a very quiet life. We seldom go out anywhere where there are lots of people except when we can’t avoid them on an airplane. We don’t go to church either. We will continue to get vaccinated every six months or so, just like with the flu vaccine.

    Around here the Asians still mask ( even the teenagers at the mall) and some of the gray haired set.

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    1. Anne, I think you could get an antibody test to tell if you had it. You were surely exposed to it with family members having it. Maybe it wouldn't matter anyway because the immunity wears off. I am debating about getting another booster. I had four vaxes total, and then the virus in December. I suppose it's best to err on the side of caution.

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    2. Katherine, the antibody test doesn’t work after a few months. So unless I had Covid without symptoms in the last three months or so a test probably wouldn’t work. I asked my doctor about it.

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  5. Stanley, I read about the possible heart issues with Pfizer vaccines and young men fairly early on. They quickly issued guidance about choosing a different vaccine for young males. I don’t think the studies were suppressed because I read about them. The vaccines didn’t do a perfect job stopping Covid but very clearly did a good job in reducing mortality rates from Covid in all but the highest risk patients with comorbities. We went with Moderna because I had read that they gave a lot of VIPs Moderna early on including Dr. Fauci, the Pope and Queen Elizabeth!

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    1. One of my sons had the Pfizer, but had no problems. The other son had Moderna. The funny thing is, the one with Pfizer never caught the virus, but he worked from home with very little outside exposure. The son with Moderna did eventually catch it. But he works in a school and has three kids who had it.

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    2. Anne, in the link I provided, the doctor shows that the early problem was somehow corrected. The later batches didn't have nearly as much side effects. I wonder what made the difference, just from a lessons-learned point of view.
      When I took the Moderna, I knew there was a risk any time you poke the immune system, the tiger within. Sometimes I think people reason in binary terms. As an engineer, I think in terms of probability and tradeoff.
      I'm sure better judgements could have been made in hindsight, but given this virus, so nasty in so many ways, I think the measures were necessary.

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    3. The Danish dr. Was apparently opposed to Denmark locking down for Covid. I don’t know if she was a Covid denier though. I couldn’t find much about her study on legitimate medical websites. But I did find stuff about the man who interviewed her. He’s not a commentator that I would trust, based on this information. Here’s a link to the wiki article.

      https://en.wikipedia.org/wiki/John_Campbell_(YouTuber)

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    4. He has asked some interesting questions.
      1. With traditional vaccines, you become immune to all parts of the virus. With mRNA, only the spikes. What difference does this make?
      2. With traditional vaccines, you are exposed to a set amount of antigens. With mRNA, the body produces the antigens. How much does this vary from person to person and does it matter?
      Perhaps the answers are out on the internet but I haven't even heard them brought up in MSM. I am merely curious. There's no doubt that I have never had a reaction to a vaccine like I did to this one. I can't even remember having had a reaction at all besides a sore arm. And even that was much more severe. To merely question and critique what was done during the pandemic is not to become an anti-vaxxer or Trumper.

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    5. Well, I am not a scientist. So I look for scientific studies that seem to be open minded without pre-determined conclusions. I spend a huge amount of time googling medical terminology! Unfortunately as we know, many studies are funded by groups with an agenda, such as pharmaceutical companies. So it takes a lot of reading. I did read a lot of the supposedly scientific anti-vax stuff, but it wasn’t convincing. However, you are right - asking questions doesn’t hurt.

      I only looked at the beginning of the video.

      I don’t get my information from videos or podcasts because of my hearing. Generated closed captions on YouTube are pretty awful and inaccurate. I was a researcher for more than 25 years, mostly in economics. I use that background to research most things, ranging from choosing the best paints for walls, to cosmetics, to medical. Pretty much everything. So I read studies, which have the advantage of providing details on how the studies were done - how participants were chosen, the characteristics of participants (ages, gender, health status etc) as well as citations and links to underlying data and studies. I can’t get that from videos or podcasts. So I did a bit of research on the two people involved with the video. Before getting the vaccine. I read a lot about the decades long development of the mRNA technology and decided that I would get the vaccine. It didn’t happen in just a year. The research for mRNA vaccine technologies had been underway for years. After doing extensive research my husband and I decided that it was a more than reasonable risk. But chose Moderna for the reasons I said earlier - it was the vaccine of choice for various VIPs, including Biden and the others I mentioned. I figured the docs would try to minimize risks to them. But obviously everyone has different reactions to medication. My husband, sons, their wives, and the seven grandchildren had minimal or no reactions. None of our friends or family had more than sore arms for a day or so. Mostly no reactions. One of the grandsons was very tired for a day. I had a mildly sore arm for about 12 hours. I’m sorry that you had a bad reaction. There is always a bell curve and unfortunately your reaction was at the extreme. I am allergic to penicillin. It can be a lifesaver for most. But it could kill me. I am at the negative extreme part of the curve for penicillin reactions. I had a cardiac arrest during an appendectomy that was probably a reaction to the anesthesia. I accept that medicine is not perfect. So I always do my homework before having a medical procedure or taking a medication, knowing that there will still be some risk, no matter how well I’ve tried to inform myself. It’s all we can do - inform ourselves and make a decision, and hope for the best.

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    6. I suppose the next decision is whether to get another COVID vaccination. It's been a year since my fourth shot. I guess I'll make a decision on that in the Fall.

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    7. Our doc recommended that we get another bivalent this summer ( our last was in October) and then the new vaccine in late fall. My husband is high risk due to age and heart failure. But we’ve not had bad side effects.

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    8. My family member who got the worst vaccine reaction was my daughter in law. She had the Johnson and Johnson one. The rest of us didn't get a severe reaction. I believe the J and J was not mRNA, she chose it because you only had to get one shot. Anyway it didn't even provide good protection, she got sick fairly soon afterwards, and her sense of taste still hasn't entirely returned. I don't know if they're even giving the J and J anymore?
      I do know that some people got quite sick on the other vaxes too, they did kind of fast forward things, but time was of the essence.

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    9. I get sick the next day after the Moderna: fever, lethargy, nausea, very sore injection point. It's nothing I can't tolerate but it's the first time I ever had such a reaction. I've heard it said that it's a good thing indicating my immune system is working, Maybe my body is very good at manufacturing the antigen and I get effectively more dosage than others. Right now, I feel pretty good and I hope it lasts for a while, at least.

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    10. I got Moderna for the first two, and then Pfizer for the most recent two(?) Honestly, I've lost track of how many I've had, but it's at least four. The most recent was at the same time as my last flu shot, a bit more than a year ago. I'll do the same again this fall unless the CDC says not to.

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  6. Betty had read much about the history of pandemics, largely because she was a medical technician during the AIDs epidemic which drastically changed medical protocols and some human behavior. Therefore, we were far less dependent upon the media for our framework
    .
    We recognized early on that the pandemic would likely last for three years, and that our isolation from it would be critical. So, we withdrew from parish life in February 2020. We welcomed Governor DeWine efforts to flatten the curve. But we were dismayed how much economic interests determined the response of public officials. Governor DeWine reopened the Ohio economy not so much because Ohio businesses wanted it, but because state revenues were plummeting.

    Catholic Bishops were quick to reopen churches in June 2020. I can remember the video of my pastor sitting in the pastoral chair inviting us all to return “home” and hinting that the “train was about to leave the station.” That changed my relationship to parochial life forever. No parish will ever be my home; they are not safe. Besides they are a business not a real community; I was time to face that fact. My house will be the center on our liturgical and communal life from now on.

    From the beginning I saw the pandemic as a three year Jesuit style formation period (two years of novitiate plus tertianship) to prepare for a truly retired life on the margins of society. “Ones withdrawn” is the literal translation of mono-anchores, or monk. I am now eighty-one; Betty is younger but with more health problems. We have no relatives nearby to support us, even those at a distance both physically and socially are not likely.

    However, we have begun the process of building our own social network. Betty convinced me that I should redo the siding on the house; it had been long neglected. It provides the perfect exterior for our ‘house church.” We are remodeling the garage to be a multipurpose center during the non-winter months. It is insolated. It will be heated, with a new light and shelve system. Perfect for raising plants in the spring, etc. We have tables that we move out into our extended L shaped driveway, like a big patio. I plan to have a computer, projector and screen to share my Divine Office website with a few people at a time. I have purchased extra copies of Bishop Barron’s monthly LOH booklets to give away to visitors. Yesterday we interviewed someone whom we plan to hire to do yard cleanup. He is Catholic; outgoing Betty handed him one the booklets.

    Betty knows one of the deacons from our parish. We are thinking of inviting him to our “garage” to share the LOH project and serve as our laison with pastoral staff. I asked Betty what happens if he asks us if we want communion for the homebound. We agree that would be OK if it were done in the context of celebration of one of the Hours. A communion service in a garage? Of course! Garages are the modern day equivalent of stables?

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