Tuesday, May 18, 2021

Will the Current USA Pandemic Incidence Continue to Decline?

 Summary

The current decline in new cases at the rate of 2% per day is not the first decline.  The January –February decline at the rate of 2.5% ended in stagnation in March.  The July-August decline at the rate of 1.5% ended in the great spike which began in mid-September.  Can these past declines help us predict what will happen in the rest of this calendar year?

Prevalence refers to proportion of persons who have a condition at or during a particular time period, whereas incidence refers to the proportion or rate of persons who develop a condition during a particular time period. All rates of new cases per day, both projected and actual, are an average of the last seven days.

The Current USA Pandemic Incidence Decline which began on April 10

On April 10 the national number of new cases per day began to decline. About two weeks later I decided the rate of two percent per day best fitted the decline. So in the following chart the projected estimates are given, along with the actual incidence for that day, and then the difference. Positive numbers indicate that the incidence exceeded the projection.  As can been seen below the actual incidence on May 15 (average of preceding seven days) was 302 cases below the projected number.  Typically when there is a smooth decline the smoothed daily variability has been within about five thousand cases on either side of the projected figure.

 

APRIL 10 (CURRENT) PANDEMIC DECLINE

Pandemic Incidence Decline Projection

 at Rate of 2% per Day

Date

Projected

Actual

Difference

April 10

73193

73193

0

May 1

47887

52747

+2835

May 15

36090

35788

-302

June 1

25599

 

 

June 15

19293

 

 

July 4

13143

 

 

July 15

10524

 

 

August 1

7465

 

 

August 15

5626

 

 

September 5

3581

 

 

September 15

3007

 

 

October 1

2221

 

 

October 15

1640

 

 

November 1

1164

 

 

November 15

877

 

 

 

The projection would bring incidence down to 25599 on June 1, then 13143 on July 4,  then 7465 on August 1 and then 3581 on Labor Day, September 5.  Ultimately it predicts below a thousand new cases a day by Thanksgiving.  So unless we are in a hot spot or a large gathering, we should be reasonably safe on July 4th, mostly safe by Labor Day and very safe by Thanksgiving. 

How likely is this to happen?   Well our last major decline which began in early January stagnated in early March. Our previous major decline which began on July 25, 2020 reversed on September 11, 2020 into the largest surge of the pandemic.


The largest and most rapid decline which began on January 9, 2021

On January 9, 2021 the national incident rate per day was 256954 new cases. A decline began which a few weeks later I estimated would be at the rate of 2.5 percent per day. The projections worked well until after March 6. There were in fact 61833 cases on that day, 409 cases lower than the predicted 62222.  By April 1 the incidence was climbing again with a new case rate of 63914, more than thirty thousand cases above the projected 32215 cases for that date.  Cases continued to climb erratically until April 10 when the next firm decline started.

JANUARY FEBRUARY PANDEMIC DECLINE

Pandemic Decline at Rate of 2.5% per Day

Date

Projected

Actual

Difference

January 9

256954

256964

0

February 1

143480

145073

+1592

February 15

100660

85593

-15067

March 1

70619

66681

-3938

March 6

62222

61833

-409

March 15

49543

55030

+5487

April 1

32215

63914

+31698

April 10

25651

73193

+47541

May 1

14696

49765

+35068

May 15

10575

35788

+25213

June 1

6876

 

 

June 15

4824

 

 

July 4

2982

 

 

July 15

2257

 

 

August 1

1468

 

 

August 15

1030

 

 

September 5

605

 

 

 

Why did the rate level stagnate with a slow erratic climb?  Most likely this was due to new faster spreading variants.  When the decline did resume it was at a 2.0% rate rather than the previous 2.5 % rate. However other factors (vaccination rate, mask wearing, social distancing, indoor vs. outdoor activity, and size of gatherings) likely played some role. 

What would have happened if the 2.5 percent per day downward trend had continued?  Cases would have been at 25651 instead of 73193 on April 10, then reached 15073 per day on May 1, and 6876 on June 1, and finally 2982 on July 4.   In other words the whole downward trend got moved back by two to three months during the stagnation period.  

The Decline that began on July 25, 2020

Back on July 25, 2020 there were 67567 cases per day. Then a decline started at the rate of 1.5 percent per day that continued until September 11th when the predicted number of new cases was to be at 32709. It was actually 31799 cases, almost a thousand lower.  What happened after that day is that everything reversed and new cases began to climb rapidly upward.

AUGUST 2020 PANDEMIC DECLINE

Pandemic Decline at Rate of 1.5% per Day

Date

Projected

Actual

Difference

July 25

67567

67567

0

August 15

49192

52901

+3709

Sept 1

38046

41231

+3184

September 11

32709

31799

-911

October 1

24177

41500

+17323

October 15

19566

53066

+33500

November 2

14906

87168

+72262

 

What would have happened had the downward trend at the rate of 1.5 percent continued?   It would have reach 24177 by October 1, and then 14906 by election eve. Trump would have been saying all during October that the virus was going away even without the vaccine.  I think he would have been re-elected.  Shortly afterward all the announcements of the vaccines would have been made.  He would have said, “Look not only is the virus going away, but we have the vaccines to keep it away.”  If the Republicans had won the House and Senate Trump would be talking about “president for life.” 

CONCLUSIONS

It is interesting that a downward trend of 1.5 percent occurred without a vaccine. The downward trend accelerated to 2.5 percent with the vaccine, but came back to 2.0 percent with the change in variants. Behavior, vaccines, and virus variants are each important in controlling the virus.

We should wary of attributing the 2.5 percent decline to the vaccine alone; up to 1.5 percent of that may have been due to behavior.  Similarly the plateau between the 2.5 percent decline and the 2.0 percent decline may have been because of behavioral changes as much as new variants.

Our predictions for what is next should include both the extreme cases of a continued 2.0 percent decline due mostly to continued vaccine rollout, and another flat plateau due to relaxation of behavioral control.  Mostly likely it will be something in between. I have calculated three additional scenarios at 1.5 percent, 1.0 percent, and 0.5 percent depending on the relative mix of vaccine rollout, variants, and behavioral control.  

PROJECTIONS

In the chart below there are five projections: The April 10 base at two percent, the May 15 base at 1.5 percent, the May 15 base at one percent, the May 15 base at 0.5 percent and the May 15 base at zero percent (i.e. a plateau).

FUTURE PANDEMIC DECLINE PROJECTIONS

Pandemic Incidence Decline Projection at Rate of

Date

April 10 2% 

May 15

1.5%

May 15

1%

May 15

0.5%

May 15

0%

May 15

36090

35788

35788

35788

35788

June 1

25599

27679

30167

32865

35788

June 15

19293

22401

26208

30637

35788

July 4

13143

16809

21652

27854

35788

July 15

10524

14235

19386

26360

35788

August 1

7465

11009

16341

24207

35788

August 15

5626

8910

14196

22566

35788

September 5

3607

6891

11380

20723

35788

September 15

3007

5577

10396

19319

35788

October 1

2221

4379

8852

17830

35788

October 15

1640

3544

7690

16621

35788

November 1

1164

2741

6482

15264

35788

November 15

877

2218

5631

14229

35788

 

PREDICTIONS

The extreme projections are unlikely to happen.  We will not likely be able to maintain the present two percent per day decline as restrictions vanish, and it is unlikely that the virus will be able to maintain its rate of infection as vaccinations increase even if the rate of vaccination is slow. Since it is unlikely that behavioral restrictions will be increased, the rate of decline will likely depend upon the rate of vaccinations.  If we make a strong effort to vaccinate people as soon as possible we will be closer to the two percent column, but if vaccinations stagnate we will be closer to the zero percent column.  We should try to be under ten thousand new cases a day before September.  We certainly don’t want the rate to be above ten thousand new cases when we get into the Thanksgiving and Christmas holidays.

  


7 comments:

  1. I don't suppose the anti-vaxers can be moved, but I think the ones who are hesitant can be encouraged, bribed, and incentivized.
    And hopefully the rest of the world can also get in a better place with vaccination rates. We should do anything we can as a nation to help that. along

    ReplyDelete
  2. DeWine's giving a million dollars a week for five weeks in a lottery to those who have had at least one shot appears to be working.

    ReplyDelete
  3. There are a couple of other factors that might play into this. One is the season - unsurprisingly, last fall the rate of new infections climbed dramatically, escalating from the Thanksgiving holidays to after the New Year. People were indoors more, and many decided to ignore the advice not to travel and not to gather with friends and family. The virus had spread to parts of America by then also, especially rural America, that had been spared the first round. Since these states were among the mask and lockdown resisters, it may be that the rate of acceleration of new cases there was even faster than in other areas. The late fall and early winter peak is the time period that claimed Tom, and also my sister-in-law's brother. I still am puzzled about Tom, as he was hyperaware of the risks and was taking such care. But I suspect my sister-in-law's brother, a sociable guy, decided that socializing during the holidays would be OK in maskless Arizona. He may have even told himself that his sister and brother-in-law had survived Covid, so if he got sick, he would too. But he didn't.

    Then there is the herd immunity factor. According to today's numbers, 37% of Americans (adult I assume) have had both doses. An even larger number have had the first, which does offer at least some protection. The decline starting in January was probably due to the expected seasonal factors after the holidays were over. But January also saw the beginning of vaccinations. Add those newly immune numbers of people to those already immune from surviving the virus, and it reinforced the braking of the rate of spread.

    Finally, there is the unknown number of covid infections that were never reported. I would not be surprised if the number of known cases (33 million as of today) is only 1/3 or 1/2 of the actual numbers of cases. We never did routine testing, and those with mild symptoms most likely were never motivated to get tested. Nobody knows for sure how long the immunity from being infected lasts, but the info I have is that it is at least six months. So, it could be that another 66 to 75 million Americans have some immunity to the disease in addition to the millions who have been vaccinated. That would reinforce the decline in infections, adding to the slowing of new cases trend caused due to seasonal factors combined with increasing numbers of the vaccinated.

    So - perhaps your optimistic scenario will play out. I just hope that we didn't jump the gun on removing the mask mandates and cause a reversal of the very hopeful rate of decline in new cases. I am also guessing that the US will reopen the country to tourism from overseas, especially since the EU is reopening to tourism starting in mid to late June in most EU countries. There will be pressure for the US to reciprocate and allow more international visitors into the country if they are dropping their bans on American visitors.

    ReplyDelete
  4. It's an astute conclusion that vaccines alone can't account for the decline we're experiencing; it's a combination of vaccines and virtuous behavior (social restrictions)

    Unfortunately, the situation now is (1) we've picked the vaccination candidate low-hanging fruit; and (2) we're lifting the social restrictions.

    Thanks to this post, I am now a pessimist. We will plateau and get stuck. Possibly very soon.

    ReplyDelete
    Replies
    1. Jim,

      You are obviously good at reading charts and numbers.

      This is how I used to prepare data for the mental health system. As much as possible I like to let the facts speak for themselves. A mentor told me never to try to sell data. No matter how much people may deny the facts, or question them they will come back to accepting them, and that will be a basis for future action.

      I intend to post a revised version of this post plus my recent one Faith and Attitudes to Vaccination and another one coming soon on our Cleveland Commonweal Local Community Blog Site

      I intend to send our thirty plus people an e-mail saying that while I expect that we can resume meetings in September (we usually get less than a dozen and we are all likely vaccinated) we need to have parish campaigns this summer to get everyone possible vaccinated. I will be forwarding my posts to pastoral staff that I know, as well as the bishop's office, and I invite them to do likewise.

      Delete
    2. If you are planning to initiate vaccination campaigns, this article might have useful information for you.

      https://www.nytimes.com/interactive/2021/05/18/opinion/covid-19-vaccine-hesitancy.html?referringSource=articleShare

      Delete
  5. The NYTimes thinks Covid is "on the run" in the US.

    https://www.nytimes.com/2021/05/21/briefing/covid-19-us-pandemic-vaccinations.html?action=click&module=Top%20Stories&pgtype=Homepage

    ReplyDelete