Thursday, March 25, 2021

Will the vaccines out run the variants?

This appears to be good news. Take a look at the article it has some nice graphs.  I  pay a lot of attention to the daily data from the NY Times. The rapid fall for the last two months leveled off into a slower fall a few weeks ago and now is either plateauing or going up again.  

U.S. COVID cases are climbing again. The same thing happened in Israel — before vaccination crushed the variants.


It’s official: After falling for more than two straight months, the average number of daily COVID-19 cases across the U.S. has begun — just barely — to rise again, inching up from a low of 54,059 earlier this week to 57,322 on Wednesday.

So is this the start of the variant-driven “fourth wave” that Americans have been fearing ever since the end of our horrific holiday surge?

The answer, reassuringly, appears to be no — at least not if America’s path out of the pandemic looks anything like Israel’s.

To date, more than a quarter of the U.S. population (25.3 percent) has received at least one dose of a safe and effective COVID-19 vaccine. In Israel, that number is more than 57 percent. Because of its rapid vaccine rollout — and because the more contagious “U.K. variant” known as B.1.1.7 that’s now spreading in the U.S. has already been dominant in Israel for months — experts have been eyeing Israel for early signs of how the pitched battle between vaccination and variants is likely to play out in America.

When Israel launched its vaccination campaign on Dec. 19, the virus was already surging; a few days later, the country entered its third national lockdown. Over the next month, however, cases continued to climb another 150 percent. By Jan. 25, B.1.1.7 had superseded all other strains in the country.

“The vaccine works against the British mutation, but the virus infection rate is much faster than the vaccine rate,” Sharon Alroy-Preis, head of public health at the Health Ministry, told the Knesset. “We are at a record number of people on ventilators. It’s unprecedented.”

Before long, the nation’s strict lockdown had its desired effect, and Israel’s curve finally began to bend downward. But that’s when researchers realized something else as well: The curve was bending even more among the first seniors to be immunized. Distancing wasn’t the only factor at play. Vaccination seemed to be working.

But despite moments during the winter when it seemed as if Israel’s case count was leveling off or even rebounding, vaccination access, eligibility and uptake continued to increase — and another wave never arrived. Now more than 50 percent of Israelis have been fully vaccinated, and the country is averaging fewer than 1,000 new daily cases for the first time since November — a number that has plummeted nearly 75 percent over the last two and a half weeks alone.

Crucially, that sharp drop in infections came after Israel partially reopened in February, and it has continued in the weeks since the country fully reopened on March 7. 

My comment: It looks like Israel did more than vaccinate, it also had lock downs that sound like they were more serious than ours have been.  It looks like we will be able to vaccinate everyone who wants it. I am not sure enough will actually take up the offer. 

 Here in the Ohio the State legislature just handcuffed the Governor's ability to issue health mandates by overriding his veto. Not sure we are safe as long as we have Republican majorities in our state legislatures. Legislatures micromanaging pandemics is not healthy. 


6 comments:

  1. I didn't watch President Biden's press conference, but I read highlights of it. He doubled his previous vaccination goal, saying that we'd already met the first one. But apparently no one asked any questions relating to COVID beyond that.
    I think we'll see some of the vaccination hesitant people getting on board when they see that others have gotten it and nothing bad happened. That's already happening to a degree.
    In our state they've just opened it up to the 50-60 age group. I am anxious to see the 40 plus age group get it; my older son is the only immediate family member who hasn't had at least one dose.
    I see that the Biden administration is doing some vaccine diplomacy with Mexico, lending them some of the AstraZenica doses which we have stockpiled. They aren't approved here yet, but tgey are in Mexico. Our people seem less likely to trust the AZ vax than the three already approved here.

    ReplyDelete
  2. I got my second dose of the Pfizer vaccine yesterday afternoon. So far no reaction other than a very mildly sore arm much like the flu vaccine shots, not even as sore as the first shot of the Pfizer vaccine.

    ReplyDelete
  3. Interesting background story about the British variant. I do hope that the scientists are right that the vaccines provide protection against them also. The Israel data are encouraging.

    https://www.reuters.com/investigates/special-report/health-coronavirus-uk-variant/

    ReplyDelete
    Replies
    1. Interesting article; good to know that the vaccine is working against that variant. And Ivar the Boneless sounds like a colorful character.
      I am worried too about the Brazilian variant, hopefully the vaccines work against that as well. Bolsonaro has monumentally, egregiously mishandled the pandemic in his country. He actually makes Trump look good by comparison, and that is pretty bad.
      It does appear that being vaccinated is better protection than actually getting COVID. So much for the belief that you can just tough it out.

      Delete
  4. The problem may not be whether or how much of a fourth wave we get right now but rather preventing fourth, fifth, sixth.... waves in the future by shutting down these virus strains around the world.

    We have more than enough vaccine lined up for the US, but there are many countries around the world which do not have enough vaccine. We need to bypass all the rules about intellectual propriety and get everyone to produce as much vaccine as possible to shut down these virus strains around the world.

    As long as the virus is mutating somewhere in the world it can always come back on us in a form that our vaccines can not stop.

    ReplyDelete
  5. Just a couple of observations:

    * Israel's population probably is similar to ours in some ways, but it is much smaller - about 10 million people, whereas the US has 330 million. 10 million people is a lot, and I don't wish to discount the complexity and difficulties the Israeli government faces in getting
    its population vaccinated. But the challenges and logistics the US faces are a magnitude more difficult because of its much larger population, and probably to some extent because of how dispersed its population is (as refrigeration requirements constrain our flexibility in distributing the vaccines). One of the primary obstacles to mass vaccination is manufacturing capacity; manufacturing 10 million or 20 million doses for Israel is less likely to run up against those manufacturing constraints than manufacturing 330 million or 660 million doses for the US.

    * In facing a "4th wave", I would expect the US experience to be what it has been in previous waves: different experiences in different parts of the country. We can see now, with our national infection rate leveling off and starting to rise, that the trend is more pronounced in some parts of the country than others. Even within my state of Illinois, the experiences in the City of Chicago and Cook County have been very different than the less populous downstate counties - the latter are doing much better in getting their people vaccinated.

    I mention this variability in infection rates because it occurs to me that our governments could collaborate on setting up vaccine "SWAT teams" to hit hot spots with intensive vaccination efforts.

    The population of the metro Chicago area is roughly the same as the entire nation of Israel. The New York metropolitan area is much larger - and I read earlier this week that that area is "heating up" again. A concerted, focused effort on that hot spot and others might prevent the 4th wave from achieving critical mass and spreading across the country.

    ReplyDelete