Friday, August 11, 2017

The Opioid Epidemic and Lake County Ohio

Rising Morbidity and Mortality Rates in Midlife Among Non-Hispanic Whites

is the original research article which I read in April. Angus Deaton, one of the co-authors is a Noble prize winner so it was unlikely to have many flaws. Anne Case and he are both at Princeton which now has an easy read version here.

The findings are pretty well summarized by the abstract which I have abridged as follows:

1) A marked increase in the all-cause mortality of middle-aged white non-Hispanic men and women in the United States between 1999 and 2013. This change was unique to the United States; no other rich country saw a similar turnaround. It reversed decades of progress in mortality.
2) This midlife mortality reversal was confined to white non-Hispanics. Black non-Hispanics and Hispanics at midlife, as well as those aged 65 and above in every racial and ethnic group, continued to see mortality rates fall.
3) This increase for middle aged whites was largely accounted for by increasing death rates from drug and alcohol poisonings, suicide, and chronic liver diseases and cirrhosis. Those with less education saw the most marked increases.
4) Rising midlife mortality rates of white non-Hispanics were paralleled by increases in midlife morbidity. Self-reported declines in health, mental health, and ability  to conduct activities of daily living, and increases in chronic pain and inability to work, as well as clinically measured deteriorations in liver function, all point to growing distress in this population.
The authors comment that the epidemic began with an increase in prescription drug use, that migrated to heroin use, augmented recently by stronger drugs. It is possible the increased drug use followed the increased morbidity and distress, however all these preceded the financial crisis. Nevertheless, it might be related to increasing despair of the economic future. The distress includes physiological (joint pain and sciatica) and psychological aspects, e.g. greater number of suicides. There are an increasing number of people on social security disability for these issues. In the paper, the authors write that "a serious concern is that those currently in midlife will age into Medicare in worse health than the elderly of today."

On June 24th there was an expert panel presentation on what is going on in Lake County. Below the break is my summary and comments on that meeting.What is going on in your part of the country, both in terms of the problem and the response?

“Heroin, Fentanyl, and Carfentanil: The Triple Threat on Our Doorstep”




The presentation was organized by the Cleveland Clinic. They have been doing these around the Cleveland area in collaboration with local drug enforcement and drug treatment officials. It was held in a parish hall; I found out about it through the parish bulletin. 

The Doctor from the Cleveland Clinic explained how the desire for patient satisfaction ratings led physicians to abandon 20 years of careful pain management, i.e. titration until the pain is gone, and err on the side of making the patient as comfortable as possible. She pointed out the United States is one of the few countries in the world that allows extensive advertising to consumers. She also said that not everyone becomes addicted but about half do.  

The representative of the  Lake County Narcotics Agency indicated that there were 49 opioid deaths in 2014 in the county, 42 in 2015, but 88 in 2016, and we are on the way to exceeding that in 2017.

Lake County has a very sophisticated crime lab, able to detect new drugs. Ohio appears to by a primary testing ground for new drugs from other countries. In the last two years they are no longer finding pure heroin; rather it is always mixed with the more powerful drugs such as Fentanyl, and Carfentanil. The last was designed to tranquilize elephants and kills people in very small doses the size of a grain of sand. Neither the sellers, nor the consumers know what they are getting anymore. However the increasing dangers have not diminished the many eager buyers and sellers.  

The Executive Director Lake County Alcohol Drug Addiction and Mental Health Services Board talked about prevention, treatment and recovery. She emphasized that treatment noncompliance in addiction was similar to Type I diabetes, asthma and high blood pressure.  She has been doing many educational presentations and expressed her willingness to give presentations no matter the size of the audience. 

I was disappointed at the turnout; I counted only about 50 people. Some of them were from the parish but many were from outside the parish, some were professionals. The pastor did encourage people to attend but did not make it a big priority. Neither he nor any the pastoral staff whom I know were there. 

I wrote an email to my own pastor; I suggested a similar meeting be held in our parish with greater attendance. He replied that the pastoral council was considering the matter and would forward my e-mail to them. They don’t meet during the summer.  Having been on the council, it is not generally a mover and a shaker.  Attendance at council meeting is open to all the parish but no one ever attends, nor are they invited. Maybe I should invite myself if they don’t reply to me after a few monthly meetings   

The national evidence shows this has been building for a decade; it is likely to last another decade at least, and looks like it is going to get much worse before beginning to get better.  It seemed to me to be a good idea to assemble some of the relevant staff and volunteers, and reach out to members of the parish who might be interested and come up with a comprehensive parish approach to this matter that would assure that all the appropriate staff, volunteers, and members who need to understand this issue have the relevant information and tools.  

There are many issues that need to be discussed. Our excessive reliance upon pills, and our uncritical reliance upon physicians. All these people are out to make money and our health is at stake. The root causes of this are economic but in very sophisticated ways. The less educated middle aged whites who are most vulnerable are the same population that voted for Trump. The Trump voters are not the people who lost their jobs but who are afraid of losing their jobs. They are probably not the people taking the drugs but they probably know a lot of people who are on drugs. 

14 comments:

  1. This comment has been removed by the author.

    ReplyDelete
  2. It seems to not be as bad out here as it is in some parts of the east, but it's still a problem. There was an episode about it on a local show here - Studio Sacramento: Pain and the Opioid Crisis

    ReplyDelete
  3. My spouse was in a bad auto accident in 2003 and has lower back and neck disk problems. He has been on a time-release Fentanyl patch ever since, and will be for the rest of his life. He obviously has an addiction, but has never felt the necessity to add to the cocktail. His MD monitor his usage monthly and periodically cuts back on the dosage slightly. He has actually reduced his intake from 150 mcg per every 2 days to 125 mcg every 2 days. If he ever tried to get off of it completely, the MD says that his HMO has a closely monitored and evidently successful program to deal with withdrawal issues. I hope we never have to experience that!

    ReplyDelete
  4. Luckily, the only back problems I've had were handled with stretching exercises. I find the thought of chronic back pain terrifying and, of course, is only a car accident away. Sorry to hear about your spouse and hope the pain management works. A friend of mine gets headaches from neck arthritis. No doubt a delayed gift from playing HS football.

    ReplyDelete
  5. There's financial despondency that can lead to drug abuse. And there's addictive personalities. I think both problems have to be addressed in different ways.

    Laws that protect workers improve wage disparity, and offer basic medical care and housing might improve abuse that stems from financial despondency.

    The problem with addictive personalities is that treatment depends on their own motivation. And most of them don't want to quit. Throwing money into treatment programs post-withdrawal is misguided, in my experience with a family full of alcoholics and addicts.

    AA and similar work as well as anything (i.e., not very well) for addicts, and they're free.

    Perhaps the next step is institutions for incorrigible addicts who are a danger to themselves and others. The idea of throwing cancer patients out on the street to fend for themselves is abhorrent. If addiction is really a disease, why do we leave addicts to their own devices, which usually involves domestic abuse, child neglect, and family impoverishment?

    ReplyDelete
  6. Sorry to hear about your spouse, Jim. I ruptured a disk in my back a few years ago - very painful. It sounds like he has a good doctor.

    It's a problem in Europe too - The Opioid Epidemic Hits The European Union

    ReplyDelete
    Replies
    1. I looked at the original study this reports. Shaky methodology. They primed the subject pool to get people who reported usage; then claim to statistically adjust that to a normal population. They used self report. That is different from death certificates.

      At least the journalistic article admits that the differences likely have more to do with culture than with genetics.

      Delete
  7. This is an epidemic; i.e. the morbidity and mortality that we are seeing is beyond what one would expect from addictive personalities or business cycles.

    It is not a crises or an emergency since it is not a pandemic. Other advanced countries are not experiencing this epidemic. Nor are Hispanics or Blacks or the elderly.

    Not only is it limited to whites, it is also more prevalent among less educated whites.

    The evidence points to it beginning in a change in physician practice and the marking of pain killers.

    While there is not evidence linking the epidemic to cyclical changes in the economy, it might be linked to long term changes in the economy. Specifically the white working class people increasing have poor prospects not only as individuals but also as a group. However Hispanics and Blacks still have an upward trajectory as individuals and as a group. The psychology of hope and expectations may be more important that absolute wealth.

    ReplyDelete
  8. Jack, yes, I think fewer people feel hopeful about the future in the white working class. They're also the ones forming militias and voting for Trump. The plants have been laying off for two or three generations now. They're having to take crappy jobs for less pay. Some feel their white entitlements are dwindling.

    ReplyDelete
  9. I would expect that addiction rates would be higher among people who worked physical jobs, simply because they would be more likely to have injuries which caused chronic pain. And since these also tend to be lower paying jobs (especially in these times of dwindling union influence) people would have feelings of discouragement about being able to better their situation. More of these people would end up on disability. Of course the Republican answer to that is that we are way too lax about disability requirements.

    ReplyDelete
  10. "Of course the Republican answer to that is that we are way too lax about disability requirements." Yeah. And soft on crime. Trump's declaration of an emergency seems to rely on the Justice Department to end this terrible, terrible thing that has been going on for many years. Many years. And it will stop, believe me.

    He was briefed, but Steve Doocy wasn't the briefer, so he probably didn't understand much.

    ReplyDelete
  11. Work with this issue every day - it is complex; multi-layered; there is no one solution. Access link below - key driver in this epidemic is PAIN MANAGEMENT. Currently, too many pharma, primary care MDs, surgeons, hospitals perform standard procedures; do no addiction screenings or life/family history and send folks home with 100-500 high dose opioids for pain vs. mandating rehab, wellness measures, counseling, etc.
    Note - 9 out of 10 surgeries in USA discharge with too many opioids prescribed compared to Europe where only 1 out of 10 meet that poor result. Newest study in US indicates that the bottom 1/3rd of medical class graduates who are now MDs account for 80% of opioid perscriptions.

    http://www.painmed.org/patientcenter/facts_on_pain.aspx#incidence

    https://nccih.nih.gov/research/statistics/NHIS/2012/pain/severity
    Citation: Nahin RL. Estimates of pain prevalence and severity in adults: United States, 2012. Journal of Pain. 2015;16(8):769-780

    ReplyDelete
    Replies
    1. To go further into what Bill said: Doctors are often told their office visits can't last more than 15 or 20 minutes by the health care system they work for. It's quicker to write a scrip than really ask what's going on. In addition, hospitals are discharging people post surgery within a day or two so they can cram in more patients. Hence they get sent home with opioids. In the olden days, you couldn't go home until you were off the hard stuff.

      Health care, like every other profit-making enterprise taken over by big biz, is on an assembly line process.

      When I take my elderly mother to the doc, she rambles and brings in many different complaints and observations. The doctor can't deal with all this info, and he doesn't know what he should pay attention to and what he needs to let go for now. He is brusque (and possibly rude) when I am not there to prompt.

      As a result, he is far more inclined to write a scrip for whatever is ailing her and send her home with it. She collected two opioid scrips last week during a crisis with back pain.

      Compare this chaos with the GP with her cardiologist brought in a specialty nurse who comes in after the exam to answer questions and do teaching. Boy, has this made a difference! The nurse is used to elderly patients and takes more time.

      My mother, who suffers from some mental health issues, left the last cardiac nurse appointment happy and anxiety free. I say prayers at night for Nurse Yvonne!

      Delete
  12. Bill, thanks for your comment. It is particularly the fact that the issue is complex that we need more attention paid to it. Fortunately in my area the responsible local officials are making them selves available to the public not just the media. Unfortunately too many people are dismissing this as not a problem that they need to be concerned about.

    One of the problems of all these prescriptions is that many people have these drugs in their medicine cabinets. Our county has a fine program in which you can drop off any drugs (prescription or non) to the local police department, no questions asked. They are all collected and safely disposed of by our narcotics people so they don't get into the landfill or the sewage or the hands of the wrong people.

    ReplyDelete